Our research is grounded in the understanding of the molecular mechanisms involved in the pathogenesis
to respiratory viruses. A multifocal approach seeks to elucidate viral-host interactions, host defense, and immunity
mediated by immune and pulmonary cell lineages. A systems biology approach to the understanding of transcriptional networks
specific to distinct epithelial and immunologic cell lineages is a common endeavor. The study of novel vaccines, antivirals,
and immune modulators is also a common endeavor. Systems biology approaches are becoming increasingly important in understanding
the complex interactions of multiple organs, tissues, and cells in the context of infectious diseases. Recent efforts are under
way to incorporate global analysis of transcriptional mechanisms using both genomic, proteomic and bioinformatic technologies
to these emerging fields.